Effects of Sodium Dodecylbenzene Sulfonate (LAS) on Acute Toxicity and Blood Biochemistry in Yellow River CarpCyprinus carpio haematopterus
TIAN Haijun1, LIU Kaifang1, REN Shengjie2
1. Fisheries College, Xinyang Agriculture and Forestry University, Xinyang 464000, China; 2. College of Marine and Biological Engineering, Yancheng Institate of Technology, Yancheng 224051, China
Abstract:The 96 h median lethal concentration (LC50) and blood physiological and biochemical indicators were investigated in Yellow River carp Cyprinus carpio haematopterus with body weight of (38.7±0.8) g exposed to surfactant sodium dodecylbenzene sulfonate (LAS) in a 1.2 m×0.6 m×0.8 m aquarium at water temperature of (21.4±0.8) ℃ through a semi-static biotoxicity test in order to explore the mechanism of physiological and biochemical toxicity of LAS on aquatic animals. It was found that LC50 of LAS to Yellow River carp was 10.27 mg/L in 24 h, 9.51 mg/L in 48 h, 9.16 mg/L in 72 h, and 8.59 mg/L in 96 h, with moderately toxicity of LAS to Yellow River carp. There were decrease in contents of plasma total protein (TP), albumin (ALB), globulin (GLB), red blood cell (RBC), white blood cell (WBC) and hemoglobin (Hb) and in plasma alkaline phosphate (ALP) activity at LAS concentration of ≥2.0 mg/L, and increase in contents of plasma urea nitrogen (BUN) and creatinine (CREA), and activities of creatine phosphokinase (CPK), alanine aminotransferase (AST) and aspartate aminotransferase (ALT) in the Yellow River carp exposed to LAS. The elevated concentration of Na+ and K+ were observed in the plasma of Yellow River carp exposed to the LAS concentration of ≥3.0 mg/L, the effect of LAS on plasma Ca2+ level being less.
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