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| Acute Toxicity of Several Conventional Drugs in Aquaculture to Juvenile Grouper Epinephelus coioides |
| CHENG Minhong,YANG Xiaoli,PANG Qiang,HUANG Jianrong,LI Zufu |
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Abstract The acute toxicity of five conventional aquacultural drugs including formaldehyde ,povidone iodine ,quaternary ammonium salt complexing iodine ,trichloroisocyanuric acid ,and CuSO4 + FeSO4 (5∶2) to juvenile grouper Epinephelus coioides were studied at a salinity of 19~21 ,pH of 8 .09~8 .30 and water temperature of (29 .5 ± 1 .5) ℃ using a static bioassay test .The results showed that the 24 h LC50 was found to be 316 .084 mg/L for formaldehyde ,54 .8527 mg/L for povidone iodine ,22 .502 mg/L for quaternary ammonium salt complexing iodine ,1 .973 mg/L for trichloroisocyanuric acid ,and 12 .984 mg/L for CuSO4 + FeSO4 (5 ∶ 2) .The 48 h LC50 was 290 .581 mg/ for formaldehyde L ,52 .3070 mg/L for povidone iodine , 21 .161 mg/L for quaternary ammonium salt complexing iodine , 1 .839 mg/L for trichloroisocyanuric acid ,and 9 .414 mg/L for CuSO4 + FeSO4 (5 ∶ 2) ,with the safe concentrations of 73 .67 mg/L ,14 .27 mg/L ,5 .614 mg/L ,0 .479 mg/L ,and 1 .485 mg/L ,respectively .The grouper showed sensitivity to these aquacultural drugs significantly . The findings suggest that formaldehyde , povidone iodine ,quaternary ammonium salt complexing iodine and trichloroisocyanuric acid could be used safely in production ,but CuSO4 +FeSO4 (5∶2) should be used carefully .
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Received: 25 February 2014
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