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| Antibacterial Activity of Chinese Herbal Medicine against Pathogenic Aeromonas caviae in Cultured Giant Salamander Andrias davidianus in vitro |
| LING Kong,DING Shihua,WU Xingzhen,JIN Juan |
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Abstract Chinese herbal medicines against pathogenic Aeromonas caviae were screened for cultured giant salamander Andrias davidianus in vitro .Effects of pH values on inhibition against A .caviae by Chinese herbal medicines were studied by agar plate diffusion method ,including the minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC) of single drug and the compounds against pathogenic A .caviae by agar double dilution method .It was found that 200 kinds of Chinese herbal medicines had different antibacterial effects on the pathogenic bacterium ,135 kinds showing to some extent antibacterial activity ,and 65 kinds showing no antibacterial activity .Terminalia chebula Retz ,Rhus chinensis Mil ,Punica granate ,Rheum palmatum and Sophora j aponica had the minimum MIC and the minimum MBC of less than 1 .0 mg/mL . Terminalia chebula Retz ,Rhus chinensis Mil ,Schisandra chinensis and Dendranthema morifolium showed inhibitory and bactericidal actions against A .caviae at pH near acidity .The findings provide a theoretical basis with exploitation of efficient ,safe and environmental friend drugs against pathogenic bacteria in giant salamander .
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Received: 25 July 2015
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