Comparison of Blood Cells in Normal and Diseased Large Yellow Croaker Larimichthys crocea with Visceral White Spot Disease
HUANG Weiqing1,2, LI Tingting1, WU Xiaoxuan1, DING Jianfa3
1. College of Marine Sciences, Ningde Normal University, Ningde 352100, China; 2. Engineering Research Center of Mindong Aquatic Product Deep-Processing, Ningde 352100, China; 3. College of Biological Sciences and Engineering, Ningde Normal University, Ningde 352100, China
Abstract：In order to investigate the structural changes of the blood cells of large yellow croaker Larimichthys crocea infected with visceral white spot disease, the blood cells of normal and diseased large yellow croaker weighing (34.13±0.34) g with visceral white spot disease were comparatively investigated for individual size and leukocyte sorting ratio under microscopic and ultramicroscopic observation. The results showed that there were five types of blood cells includingerythrocytes, neutrophils, lymphocytes, thrombocytes, and monocytes in large yellow croaker. The erythrocytes of large yellow croakerinfected with visceral white spot disease were structurally characterized by disintegration of the nucleus, cleavage of the nucleolus into microsomes, or deep staining of the nucleus, deformation of the nuclear membrane, folds and cristae, and condensed, deep staining of the cytoplasm, with the morphology of a pike shape or an irregular type. There were significantly smaller neutrophils, lymphocytes and thrombocytes in the infected fish than those in the normal group (P<0.05), with the significantly larger ratio of the long diameter to the short diameter of erythrocytes, lymphocytes and thrombocytes than those in the normal group (P<0.05). The proportions of lymphocytes (15.67±1.27)% and thrombocytes (19.75±1.02)% were shown to be significantly reduced (P<0.05) in the fish infected with visceral white spot disease, while the proportions of neutrophils (13.86±3.12)% and monocytes (30.70±1.38)% were significantly increased (P<0.05) compared with the normal group. The findings provide theoretical basis for the diagnosis and prevention of visceral white spot disease.
黄伟卿, 李婷婷, 武小宣, 丁建发. 正常与感染内脏白点病大黄鱼的血细胞比较研究[J]. 水产科学, 2026, 45(2): 314-320.
HUANG Weiqing, LI Tingting, WU Xiaoxuan, DING Jianfa. Comparison of Blood Cells in Normal and Diseased Large Yellow Croaker Larimichthys crocea with Visceral White Spot Disease. Fisheries Science, 2026, 45(2): 314-320.
2026, Vol. 45 
