|
|
|
| 常见海洋动物皂苷生物活性的研究进展 |
| 姜苹哲1,2,3, 高杉1, 蒋经伟1, 肖瑶1, 张高华1, 赵亮1, 陈仲1, 徐永平2,3, 李淑英2,3, 周遵春1 |
1.辽宁省海洋水产科学研究院,辽宁 大连 116023;
2.大连赛姆生物工程技术有限公司博士后工作站,辽宁 大连 116620;
3.辽宁省噬菌体应用工程技术研究中心,辽宁 大连 116620 |
|
| Research Progress on Biological Activity of Common Saponins from Marine Animals: a Review |
| JIANG Pingzhe1,2,3, GAO Shan1, JIANG Jingwei1, XIAO Yao1, ZHANG Gaohua1, ZHAO Liang1, CHEN Zhong1, XU Yongping2,3, LI Shuying2,3, ZHOU Zunchun1 |
1. Liaoning Ocean and Fisheries Science Research Institute, Dalian 116023, China;
2. Postdoctoral Workstation ofDalian SEM Bio-Engineering Technology Co., Ltd., Dalian 116620, China;
3. Technology Innovation Center for PhageApplication of Liaoning Province, Dalian 116620, China |
| 引用本文: |
姜苹哲, 高杉, 蒋经伟, 肖瑶, 张高华, 赵亮, 陈仲, 徐永平, 李淑英, 周遵春. 常见海洋动物皂苷生物活性的研究进展[J]. 水产科学, 2023, 42(2): 339-346.
JIANG Pingzhe, GAO Shan, JIANG Jingwei, XIAO Yao, ZHANG Gaohua, ZHAO Liang, CHEN Zhong, XU Yongping, LI Shuying, ZHOU Zunchun. Research Progress on Biological Activity of Common Saponins from Marine Animals: a Review. Fisheries Science, 2023, 42(2): 339-346.
|
|
|
|
| 链接本文: |
| http://www.shchkx.com/CN/10.16378/j.cnki.1003-1111.21246 或 http://www.shchkx.com/CN/Y2023/V42/I2/339 |
[1]MUGFORD S T, OSBOURN A. Saponin synthesis and function[M]. New York:Springer,2013:405-424.
[2]VINCKEN J P, HENG L, DE GROOT A, et al. Saponins, classification and occurrence in the plant kingdom[J].Phytochemistry,2007,68(3):275-297.
[3]BAHRAMI Y, FRANCO C M M. Structure elucidation of new acetylated saponins, Lessoniosides A, B, C, D, and E, and non-acetylated saponins, Lessoniosides F and G, from the viscera of the sea cucumber Holothuria lessoni[J].Marine Drugs,2015,13(1):597-617.
[4]MOSES T, PAPADOPOULOU K K, OSBOURN A. Metabolic and functional diversity of saponins, biosynthetic intermediates and semi-synthetic derivatives[J].Critical Reviews in Biochemistry and Molecular Biology,2014,49(6):439-462.
[5]XIAO G Z, SHAO X F, ZHU D P, et al. Chemical synthesis of marine saponins[J]. Natural Product Reports,2019,36(5):769-787.
[6]ZHAO Y C, XUE C H, ZHANG T T, et al. Saponins from sea cucumber and their biological activities[J].Journal of Agricultural and Food Chemistry,2018,66(28):7222-7237.
[7]YANG Y J, LI X N, SUN L N. Triterpenoid saponin biosynthesis genes and their expression patterns during the development of sea cucumber Apostichopus japonicus[J].Journal of Oceanology and Limnology,2021,39(6):2295-2308.
[8]MINALE L, IORIZZI M, PALAGIANO E, et al. Steroid and triterpenoid oligoglycosides of marine origin[J].Advances in Experimental Medicine and Biology,1996,404:335-356.
[9]KICHA A A, KALINOVSKII A I, IVANCHINA N V, et al. Minor steroidal triglycoside planciside D from the tropical starfish Acanthaster planci[J].Chemistry of Natural Compounds,2014,50(6):1032-1036.
[10]IVANCHINA N V, KICHA A A, STONIK V A. Steroid glycosides from marine organisms[J].Steroids,2011,76(5):425-454.
[11]KALININ V I, AVILOV S A, SILCHENKO A S, et al. Triterpene glycosides of sea cucumbers (Holothuroidea, Echinodermata) as taxonomic markers[J].Natural Product Communications,2015,10(1):21-26.
[12]刘桂英,王旭达,葛坤,等.响应面法优化提取仿刺参中海参皂苷工艺[J].水产科学,2021,40(6):810-817.
[13]MAH C L, BLAKE D B. Global diversity and phylogeny of the Asteroidea (Echinodermata)[J].PLoS One,2012,7(4):e35644.
[14]王彩理,赵丽静,王平,等.海星安全性及其功能性研究[J].食品安全导刊,2019(21):181-183.
[15]DONG G, XU T, YANG B, et al. Chemical constituents and bioactivities of starfish[J].Chemistry and Biodiversity,2011,8(5):740-791.
[16]STONIK V A, KICHA A A, MALYARENKO T V, et al. Asterosaponins:structures, taxonomic distribution, biogenesis and biological activities[J].Marine Drugs,2020,18(12):584.
[17]CASAPULLO A, FINAMORE E, MINALE L, et al. Starfish saponins, part 49: new cytotoxic steroidal glycosides from the starfish Fromia monilis[J].Journal of Natural Products,1993,56(1):105-115.
[18]周鹏,顾谦群,王长云.海星皂甙及其他活性成分研究概况[J].海洋科学,2000,24(2):35-37.
[19]IVANCHINA N V, KICHA A A, KALINOVSKY A I, et al. Hemolytic polar steroidal constituents of the starfish Aphelasterias japonica[J].Journal of Natural Products,2000,63(8):1178-1181.
[20]CROFT J A, HOWDEN M E. Isolation and partial characterization of a steroidal saponin from the starfish Patiriella calcar[J].Comparative Biochemistry and Physiology Part B, Comparative Biochemistry,1974,48(4):535-543.
[21]杜磊.海参和海星脑苷脂抗肿瘤及改善癌症恶病质作用的研究[D].青岛:中国海洋大学,2012.
[22]LAZZARA V, ARIZZA V, LUPARELLO C, et al. Bright spots in the darkness of cancer:a review of starfishes-derived compounds and their anti-tumor action[J].Marine Drugs,2019,17(11):617.
[23]KATANAEV V L, DI FALCO S, KHOTIMCHENKO Y. The anticancer drug discovery potential of marine invertebrates from Russian Pacific[J].Marine Drugs,2019,17(8):474.
[24]WANG W H, LI F M, HONG J, et al. Four new saponins from the starfish Certonardoa semiregularis[J].Chemical and Pharmaceutical Bulletin,2003,51(4):435-439.
[25]MALYARENKO T V, KICHA A A, IVANCHINA N V, et al. Asterosaponins from the far eastern starfish Leptasterias ochotensis and their anticancer activity[J].Steroids,2014,87:119-127.
[26]IVANCHINA N V, KALINOVSKY A I, KICHA A A, et al. Two new asterosaponins from the far eastern starfish Lethasterias fusca[J].Natural Product Communications,2012,7(7):853-858.
[27]THAO N P, CUONG N X, LUYEN B T T, et al. Anti-inflammatory asterosaponins from the starfish Astropecten monacanthus[J].Journal of Natural Products,2013,76(9):1764-1770.
[28]DE MARINO S, MINALE L, ZOLLO F, et al. ChemInform abstract:starfish saponins.part 54.cytotoxic asterosaponins from an Antarctic starfish of the family Echinasteridae[J].ChemInform,2010,28(9):no.
[29]王兵,郑意端.海星总皂苷抗肿瘤作用的实验研究[J].中草药,2001,32(3):244-245.
[30]程光,张赟,章翔,等.面包海星皂苷-1对恶性胶质瘤细胞系U87MG增殖抑制的体外研究[J].脑与神经疾病杂志,2008,16(5):575-578.
[31]NOGUCHI Y, HIGUCHI R, MARUBAYASHI N, et al. Biologically active glycosides from Asteroidea, XII.steroid oligoglycosides from the starfish Asterina pectinifera Müller et troschel, 1 structures of two new sapogenins and two new oligoglycoside sulfates:pectinioside A and pectinioside B[J].Liebigs Annalen Der Chemie,1987,1987(4):341-348.
[32]DUBOIS M A, HIGUCHI R, KOMORI T, et al. Biologically active glycosides from Asteroidea, ⅩⅥ .steroid oligoglycosides from the starfish Asterina pectinifera Müller et Troschel, 3 structures of two new oligoglycoside sulfates, pectiniosides E and F, and biological activities of the six new pectiniosides[J].Liebigs Annalen Der Chemie,1988,1988(9):845-850.
[33]TANG H F, YI Y H, LI L, et al. Asterosaponins from the starfish Culcita novaeguineae and their bioactivities[J].Fitoterapia,2006,77(1):28-34.
[34]QIU P C, LU Y Y, ZHANG S, et al. Reduction of SCUBE3 by a new marine-derived asterosaponin leads to arrest of glioma cells in G1/S[J]. Oncogenesis,2020,9(8):71.
[35]赵君,赵晶,樊廷俊,等.水溶性海星皂苷的分离纯化及其抗肿瘤活性研究[J].山东大学学报(理学版),2013,48(1):30-35.
[36]TANG H F, CHENG G, WU J, et al. Cytotoxic asterosaponins capable of promoting polymerization of tubulin from the starfish Culcita novaeguineae[J].Journal of Natural Products,2009,72(2):284-289.
[37]PALAGIANO E, ZOLLO F, MINALE L, et al. Downeyoside A and B, two new sulphated steroid glucuronides from the starfish Henricia downeyae[J].Tetrahedron,1995,51(45):12293-12300.
[38]PALAGIANO E, ZOLLO F, MINALE L, et al. Isolation of 20 glycosides from the starfish Henricia downeyae, collected in the gulf of Mexico[J].Journal of Natural Products,1996,59(4):348-354.
[39]VERBIST J F. Pharmacological effects of compounds from echinoderms[M]// JANGOUX M, LAWRENCE J M. Echinoderm Studies. Boca Raton:CRC Press,2020:111-186.
[40]ANDERSSON L, BOHLIN L, IORIZZI M, et al. Biological activity of saponins and saponin-like compounds from starfish and brittle-stars[J].Toxicon,1989,27(2):179-188.
[41]KICHA A A, KALINOVSKY A I, IVANCHINA N V, et al. New steroid glycosides from the deep-water starfish Mediaster murrayi[J].Journal of Natural Products,1999,62(2):279-282.
[42]刘文杰,周培根.多棘海盘车皂甙抗菌活性研究[J].天然产物研究与开发,2005,17(3):283-286.
[43]樊廷俊,张铮,袁文鹏,等.水溶性海星皂苷的分离纯化及其抗真菌活性研究[J].山东大学学报(理学版),2008,43(9):1-5.
[44]CHLUDIL H D, SELDES A M, MAIER M S. Antifungal steroidal glycosides from the Patagonian starfish Anasterias minuta:structure-activity correlations[J].Journal of Natural Products,2002,65(2):153-157.
[45]郭承华,董新伟,贺君,等.海燕皂苷的抗炎活性的初步研究[J].中国生化药物杂志,2010,31(4):259-260.
[46]XIA J M, MIAO Z, XIE C L, et al. Chemical constituents and bioactivities of starfishes:an update[J].Chemistry and Biodiversity,2020,17(1):e1900638.
[47]董黎明,陈思迪,刘仲娜.海星活性成分研究进展[J].科技信息(科学教研),2008(25):330.
[48]任晶,杨桂文,安利国.海星皂甙与海参皂甙研究进展[J/OL].中华实用医药杂志,2006,6(7). https://www.39kf.com/cooperate/qk/practicalmedication/0607/2006-08-20-238118.shtml.
[49]GOLDSMITH L. Pharmacological evaluation of an asterosaponin extract from Asterias forbesi (desor)[D].Kingston: University of Rhode Island,1975.
[50]赵学敏.本草纲目拾遗[J].北京:中国中医药出版社,1998.
[51]钟静诗,张健,刘芳,等.海参皂苷生物活性及其分子机制研究进展[J].食品与机械,2021,37(3):180-186.
[52]赵芹.海参胶原蛋白多肽抗氧化活性的研究[D].青岛:中国海洋大学,2008.
[53]MONDOL M A M, SHIN H J, RAHMAN M A, et al. Sea cucumber glycosides:chemical structures, producing species and important biological properties[J].Marine Drugs,2017,15(10):317.
[54]HOANG L, LE THI V, TRAN THI HONG H, et al. Triterpene glycosides from the Vietnamese sea cucumber Holothuria edulis[J].Natural Product Research,2020,34(8):1061-1067.
[55]赵超绮,杨文君,王元香,等.革皮氏海参总皂苷提取物抗肿瘤作用研究[J].食品工业科技,2017,38(3):353-356.
[56]赵芹,薛长湖,杨玉红,等.海参皂苷Echinoside A和Ds-echinoside A对C57BL/6小鼠黑色素瘤B16自发性肺转移的影响[J].食品科学,2012,33(9):230-234.
[57]刘永平.海参皂苷抑制肿瘤细胞生长机制的研究[J].当代医药论丛,2018,16(7):51-52.
[58]ZHANG X M, HAN L W, SHENG W L, et al. Two novel holostane-type glycosides from the viscera of sea cucumber Apostichopus japonicus with antitumor activities[J].Revue Roumaine De Chimie,2019,64(4):353-259.
[59]NGUYEN B C Q, YOSHIMURA K, KUMAZAWA S, et al. Frondoside A from sea cucumber and nymphaeols from Okinawa propolis:natural anti-cancer agents that selectively inhibit PAK1 in vitro[J].Drug Discoveries and Therapeutics,2017,11(2):110-114.
[60]ZHANG S L, LI L, YI Y H, et al. Philinopsides E and F, two new sulfated triterpene glycosides from the sea cucumber Pentacta quadrangularis[J].Natural Product Research,2006,20(4):399-407.
[61]DARYA M, SAJJADI M M, YOUSEFZADI M, et al. Antifouling and antibacterial activities of bioactive extracts from different organs of the sea cucumber Holothuria leucospilota[J].Helgoland Marine Research,2020,74(7):991-997.
[62]丛日山,袁文鹏,樊廷俊,等.仿刺参水溶性海参皂苷的分离制备及抗真菌活性的研究[J].中国海洋大学学报(自然科学版),2006,36(6):959-964.
[63]袁文鹏,丛日山,杨秀霞,等.水溶性海参皂苷的分离纯化及其抗真菌活性研究[J].山东大学学报(理学版),2007,42(5):69-73.
[64]MUNIAIN C, CENTURIÓN R, CAREAGA V P, et al. Chemical ecology and bioactivity of triterpene glycosides from the sea cucumber Psolus patagonicus (Dendrochirotida:Psolidae)[J].Journal of the Marine Biological Association of the United Kingdom,2008,88(4):817-823.
[65]KALININ V I, AMININ D L, AVILOV S A, et al. Triterpene glycosides from sea cucmbers (Holothurioidea, Echinodermata).biological activities and functions[J].Studies in Natural Products Chemistry,2008,35:135-196.
[66]American Diabetes Association. Diagnosis and classification of diabetes mellitus[J].Diabetes Care, 2012, 35(Suppl 1): S64-S71.
[67]GUARIGUATA L, WHITING D, WEIL C, et al. The International Diabetes Federation diabetes atlas methodology for estimating global and national prevalence of diabetes in adults[J].Diabetes Research and Clinical Practice,2011,94(3):322-332.
[68]CREE-GREEN M, TRIOLO T M, NADEAU K J. Etiology of insulin resistance in youth with type 2 diabetes[J].Current Diabetes Reports,2013,13(1):81-88.
[69]MARTIN B C, WARRAM J H, KROLEWSKI A S, et al. Role of glucose and insulin resistance in development of type 2 diabetes mellitus:results of a 25-year follow-up study[J].The Lancet,1992,340(8825):925-929.
[70]温敏,王佳慧,刘丰海,等.海参皂苷对自发性糖尿病小鼠的降血糖作用[J].食品工业科技,2013,34(22):149-152.
[71]HU X Q, LI Z J, XUE Y, et al. Dietary saponins of sea cucumber ameliorate obesity,hepatic steatosis,and glucose intolerance in high-fat diet-fed mice[J].Journal of Medicinal Food,2012,15(10):909-916.
[72]NATHAN M, RESEA P. Long-term effects of lifestyle intervention or metformin on diabetes development and microvascular complications over 15-year follow-up:the Diabetes Prevention Program Outcomes Study[J].The Lancet Diabetes and Endocrinology,2015,3(11):866-875.
[73]CHUMPHOOCHAI K, CHALORAK P, SUPHAMUNGMEE W, et al. Saponin-enriched extracts from body wall and Cuvierian tubule of Holothuria leucospilota reduce fat accumulation and suppress lipogenesis in Caenorhabditis elegans[J].Journal of the Science of Food and Agriculture,2019,99(8):4158-4166.
[74]WANG Y M, WANG J H, YANAGITA R C, et al. Effects of two sulfated triterpene saponins echinoside A and holothurin A on the inhibition of dietary fat absorption and obesity reduction[J].Bioscience, Biotechnology, and Biochemistry,2014,78(1):139-146.
[75]GUO L, GAO Z Y, ZHANG L Q, et al. Saponin-enriched sea cucumber extracts exhibit an antiobesity effect through inhibition of pancreatic lipase activity and upregulation of LXR-β signaling[J].Pharmaceutical Biology,2016,54(8):1312-1325.
[76]SHARMIN F, KOYAMA T, KOYAMA H, et al. Cholesterol-binding ability of saponin from Japanese starfish[J].Journal of Food Science and Technology,2021,58(8):3056-3064.
[77]HAWAS U W, ABOU EL-KASSEM L T, SHAHER F M, et al. Sulfated triterpene glycosides from the Saudi red sea cucumber Holothuria atra with antioxidant and cytotoxic activities[J].Thalassas:an International Journal of Marine Sciences,2021,37(2):817-824.
[78]王静凤,傅佳,王玉明,等.革皮氏海参皂苷对小鼠免疫功能的调节作用[J].中国海洋大学学报(自然科学版),2010,40(2):28-32.
[79]王晓红,李媛媛,戴宇峰,等.海参皂苷对去卵巢小鼠骨密度的改善作用及机制[J].食品科学,2019,40(5):124-129.
[80]CHALORAK P, JATTUJAN P, NOBSATHIAN S, et al. Holothuria scabra extracts exhibit anti-Parkinson potential in C. elegans :a model for anti-Parkinson testing[J].Nutritional Neuroscience,2018,21(6):427-438.
[81]MALAIWONG N, CHALORAK P, JATTUJAN P, et al. Anti-Parkinson activity of bioactive substances extracted from Holothuria leucospilota[J].Biomedicine and Pharmacotherapy,2019,109:1967-1977.
[82]甄静荣,丛建森,刘艳萍,等.金氏真蛇尾皂苷的抗氧化和抑菌活性研究[J].食品科技,2015,40(6):285-289.
[83]刘艳萍.紫蛇尾(Ophiopholis mirabilis)皂苷制备工艺及抑菌和抗氧化作用研究[D].烟台:烟台大学,2015.
[84]HAUG T, KJUUL A K, STYRVOLD O B, et al. Antibacterial activity in Strongylocentrotus droebachiensis (Echinoidea), Cucumaria frondosa (Holothuroidea), and Asterias rubens (Asteroidea)[J].Journal of Invertebrate Pathology,2002,81(2):94-102.
[85]JOMORI T, SHIROYAMA S, ISE Y, et al. Scrobiculosides A and B from the deep-sea sponge Pachastrella scrobiculosa[J].Journal of Natural Medicines,2019,73(4):814-819.
[86]SHIN J, LEE H S, WOO L, et al. New triterpenoid saponins from the sponge Erylus nobilis[J].Journal of Natural Products,2001,64(6):767-771.
[87]齐君,邵长伦,王长云.短指软珊瑚Sinularia sp.中具有细胞毒活性的甾体和甾体皂苷[G]//2012年中国药学大会暨第十二届中国药师周论文集.南京:中国药学会,2012:1-6.
[88]OSBOURN A, GOSS R J M, FIELD R A. The saponins:polar isoprenoids with important and diverse biological activities[J].Natural Product Reports,2011,28(7):1261-1268.
[89]THIMMAPPA R, GEISLER K, LOUVEAU T, et al. Triterpene biosynthesis in plants[J].Annual Review of Plant Biology,2014,65:225-257. |
| [1] |
汤伟, 王祺, 张军, 李佳欣, 邢炜, 何增国. 耐低温降解菌Bacillus mobilis 10的生物学特性及其对海参养殖水质的净化作用[J]. 水产科学, 2024, 43(6): 885-893. |
| [2] |
刘桂英, 刘煜珺, 张瑜洋, 吴金浩, 宋伦, 周遵春, 熊爽, 王政. 海参皂苷分离纯化、结构分析及活性的研究进展[J]. 水产科学, 2023, 42(1): 147-156. |
| [3] |
于宇, 李冰, 郭广鑫, 任贻超. 不同食物组分对大红海参生长和脂肪酸组成的影响[J]. 水产科学, 2022, 41(1): 85-91. |
| [4] |
刘桂英, 王旭达, 葛坤, 胡超魁, 吴金浩, 李爱, 郑杰, 周遵春. 响应面法优化提取仿刺参中海参皂苷工艺[J]. 水产科学, 2021, 40(6): 810-817. |
| [5] |
冯永勤, 翁文明, 方再光, 王怀洪, 王世锋, 廖经球, 周永灿. 糙海参苗种规模化繁育技术研究[J]. 水产科学, 2021, 40(5): 750-756. |
| [6] |
韩梓琪, 李雨晴, 任丹丹, 何云海, 周慧, 汪秋宽. 低分子褐藻聚糖硫酸酯寡糖的研究进展[J]. 水产科学, 2021, 40(3): 452-460. |
| [7] |
魏亚南, 张东升, 林青, 孙广伟, 雷兆霖, 张津源, 郭超, 陈济丰, 周玮. 3种水质调控方式下参池沉积物酶活性的比较研究[J]. 水产科学, 2020, 39(2): 193-199. |
| [8] |
侯昊晨, 张芸, 孙德林, 杨秋颖, 刘昱彤. 海参加工业清洁生产评价指标体系的构建[J]. 水产科学, 2020, 39(1): 129-134. |
| [9] |
杨蕊，吴开畅，于刚，温为庚，陈旭，赵旺，叶乐. 养殖模式对方斑东风螺生长及主要环境因子的影响[J]. 水产科学, 2019, 38(5): 610-615. |
| [10] |
胡月，彭雍博，张雪楠，王俊鑫，何云海，汪秋宽. 松藻主要生物活性物质研究进展[J]. 水产科学, 2019, 38(1): 127-134. |
| [11] |
吴雅清，许瑞安. 可口革囊星虫研究进展[J]. 水产科学, 2018, 37(6): 855-861. |
| [12] |
丛瑶，宋悦凡，汪秋宽. 褐藻多糖硫酸酯降解及其产物活性研究进展[J]. 水产科学, 2017, 36(5): 674-682. |
| [13] |
彭雍博，汪秋宽，任丹丹，宋悦凡. 铜藻主要活性物质的提取及其功能[J]. 水产科学, 2017, 36(4): 531-537. |
| [14] |
刘天红,李红艳,吴志宏,李晓,孙元芹,卢珺,姜晓东,王颖. 响应面法优化罗氏海盘车生殖腺皂甙脱除技术研究[J]. 水产科学, 2016, 35(6): 639-643. |
| [15] |
陈明强,张立,杨学明,江林源,黄光华,李有宁. 海上网箱培育大规格糙海参苗试验[J]. 水产科学, 2015, (9): 621-624. |
|
|
|
|
2023, Vol. 42 
